JNK Signalling Pathway



By

Publisher: Eurekah.com, Inc.
Number Of Pages: 97
Publication Date: 2006-02-21
Sales Rank: 2965423
ISBN / ASIN: 1587061201
EAN: 9781587061202


Table of Contents


Preface
1 The Structure of the Type 1 Insulin-Like Growth Factor Receptor
2 Structure and Function of the IGF-1 and Mannose 6-Phosphate/IGF-2 Receptors 22
3 IGFBPs - Gene and Protein Structure 48
4 Regulation of Insulin-Like Growth Factor-I Gene Expression 64
5 The Many Levels of Control of IGF-II Expression 91
6 IGF-I Receptor Signaling in Health and Disease 104
7 Insulin-Like Growth Factor-I Stimulation of Growth: Autocrine, Paracrine and/or Endocrine Mechanisms of Action? 121
8 Insulin-Like Growth Factor 1 (IGF1) and Brain Development 137
9 IGFs and the Nervous System 158
10 The Insulin-Like Growth Factors in Mammary Development and Breast Cancer 188
11 The Insulin-Like Growth Factor System and Bone 206
12 IGFBP-5, a Multifunctional Protein, Is an Important Bone Formation Regulator 219
13 IGF Action and Skeletal Muscle 235
14 Insulin-Like Growth Factor-I and the Kidney 244
15 IGF-Independent Effects of the IGFBP Superfamily 262
16 Functional Relationships between Transforming Growth Factor-[beta] and the Insulin-Like Growth Factor Binding Proteins 281
17 Insulin-Like Growth Factor Binding Proteins (IGFBPs) and Apoptosis 294
18 The Role of Insulin-Like Growth Factor-1 and Extracellular Matrix Protein Interaction in Controlling Cellular Responses to This Growth Factor 304
19 Epidemiologic Approaches to Evaluating Insulin-Like Growth Factor and Cancer Risk 317
20 IGF-I, Insulin and Cancer Risk: Linking the Biology and the Epidemiology 338
21 The Molecular Basis of IGF-I Receptor Gene Expression in Human Cancer 346
22 Antisense and Triple Helix Strategies in Basic and Clinical Research: Challenge for Gene Therapy of Tumors Expressing IGF-I 357
23 The IGF System in Breast Cancer 367
24 The Role of the IGF System in Prostate Cancer 385
25 IGFs and Sarcomas 390
26 IGFs and Epithelial Cancer 399
27 Insulin-Like Growth Factors and Hematological Malignancies 410
28 Metabolic Effects of Insulin-Like Growth Factor I and Growth Hormone in vivo: A Comparison 423
29 Insulin-Like Growth Factor II (IGF-II) and Non-Islet Cell Tumor Hypoglycemia (NICTH) 434
30 Diabetes 441
31 Insulin-Like Growth Factors in Critical Illness 457
32 Laron Syndrome: Primary GH Insensitivity or Resistance 467
Index


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Neuro-Oncology of CNS Tumors



Publisher: Springer
Number Of Pages: 706
Publication Date: 2005-12-16
Sales Rank: 216155
ISBN / ASIN: 3540258337
EAN: 9783540258339

Book Description:

Diagnosis and treatment modalities for neuro-oncologic diseases have made considerable advances in recent years. There is hardly a segment of the field of solid tumours that is experiencing such dynamic development with regard to basic scientific findings and clinical results. In the present book the world's leading experts have compiled the current practice-relevant knowledge of neuro-oncologic deseases. The book's clear structure and the uniform presentation of all chapters make this volume a valuable reference, especially for practice-oriented activities, allowing swift access to information about current treatment standards. Hence it will be of great value to both clinicians and researchers.


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Thyroid Cancer



Publisher: Springer
Number Of Pages: 363
Publication Date: 2005-08-05
Sales Rank: 2139039
ISBN / ASIN: 3540223096
EAN: 9783540223092

Book Description:

Thyroid Cancer describes all current diagnostic techniques, including FDG-PET and MRI. In recent years these modalities have documented hitherto hidden radioiodine-negative metastases, thus improving surgical therapy. The whole gamut of treatment, including surgery, radioiodine therapy, percutaneous radiation therapy and medical management, is covered. In some 10% of differentiated thyroid cancers, the well-known treatment tools of surgery and radioiodine therapy are not sufficient. New treatment modalities such as high-dose radioiodine therapy, redifferentiation therapy with retinoic acid and recombinant TSH are therefore highlighted. In a special section devoted to medullary thyroid cancer, new imaging procedures such as octreotide scintigraphy are described. The second edition includes two new chapters, on I-124 PET and dosimetry. Other chapters have been modified particularly in view of the new UICC classification, with special regard to the definition of T1 tumors.



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Cancer



Publisher: Springer
Number Of Pages: 296
Publication Date: 2007-04
Sales Rank:
ISBN / ASIN: 3540331190
EAN: 9783540331193
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The Chemotherapy Source Book



Summary:
...the most current and comprehensive reference on cancer chemotherapy, it brings together pharmacologic and patient management information in one source that practitioners can consult for any question in the delivery of chemotherapy.
Book Info
Univ. of Missouri, Columbia. Comprehensive reference covers principles of chemotherapy, chemotherapeutic drugs, the management of drug toxicity, drug administration, therapy of specific solid tumors, and therapy of hematologic malignancies. For residents and practicing oncologists. Previous edition: c1996. DNLM: Neoplasms--drug therapy


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Vascular Embolotherapy: A Comprehensive ApproachVolume 2: Oncology, Trauma, Gene Therapy, Vascular Malformations, and Neck


Publisher: Springer
Number Of Pages: 338
Publication Date: 2006-04-11
Sales Rank: 1237082
ISBN / ASIN: 3540214917
EAN: 9783540214915

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Urological Cancers in Clinical Practice


Publisher: Springer
Number Of Pages: 288
Publication Date: 2006-12-15
Sales Rank: 3595086
ISBN / ASIN: 1846284643
EAN: 9781846284649
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New Technologies in Radiation Oncology

Publisher: Springer
Number Of Pages: 464
Publication Date: 2006-07-26
Sales Rank: 66862
ISBN / ASIN: 3540003215
EAN: 9783540003212
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The Gale Encyclopedia of Cancer


ISBN: 0787656097
Author: Gale
Hardcover: 1239 pages; Dimension: 0.00 x 0.00 x 0.00 inches
Publisher: Gale Group; 1st edition (December 15, 2001)
Language: English
URL: http://www.amazon.com/exec/obidos/re...N%2F0787656097
Cover


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Handbook of Cancer Vaccines



Publisher: Humana Press
Number Of Pages: 608
Publication Date: 2004-01-28
Sales Rank: 1492342
ISBN / ASIN: 1588292096
EAN: 9781588292094



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Integration/Interaction of Oncologic Growth



Publisher: Springer
Number Of Pages: 454
Publication Date: 1899-12-31
Sales Rank: 3863397
ISBN / ASIN: 140203413X
EAN: 9781402034138


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Breast Cancer: Atlas of Clinical Oncology

Publisher: B.C. Decker
Number Of Pages: 294
Publication Date: 2000-02-15
Sales Rank: 2099519
ISBN / ASIN: 1550091123
EAN: 9781550091120
Binding: CD-ROM
Manufacturer: B.C. Decker
Studio: B.C. Decker
Average Rating:
Total Reviews:
Book Description:

Part of the American Cancer Society's acclaimed Atlas of Clinical Oncology series, this volume offers an expert overview of breast cancer. Topics range from epidemiology and genetics to diagnosis, management and reconstruction. Post-treatment care, as well as male breast cancer, is also discussed.

Key Features:
- More than 300 color illustrations, photographs, and radiographs show tumors as they manifest
- Discusses the latest techniques, such as image-directed biopsy and sentinel node biopsy
- Includes contributions from leading surgeons, radiation oncologists, medical oncologists, and gynecologists
- Accompanied by a CD-ROM with the complete text and illustrations of the book, in fully searchable PDF files
- Images can be downloaded for lectures and presentations
Audience: Students and practitioners in surgery, oncology, and gynecology, radiation oncology


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Cancer Risk Assessment


Publisher: Informa Healthcare
Number Of Pages: 792
Publication Date: 2005-05-24
Sales Rank: 1044627
ISBN / ASIN: 0824729846
EAN: 9780824729844
Binding: Hardcover
Manufacturer: Informa Healthcare
Studio: Informa Healthcare
Average Rating: 5
Total Reviews: 1
Book Description:
The assessment of cancer risk is a complex process that requires the examination of etiological agents, real-world environments, and individual rates of exposure. This reference offers practical approaches to determine cancer risk in individuals, groups of exposed persons, and the general public in relation to individual genetic and acquired susceptibilities

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